Protease-Activated Receptors and Platelet Activation
Published: 12.06.2025, 15:41:00Protease‐activated receptors (PARs) play a central role in platelet activation and thrombosis. These G protein‐coupled receptors are activated through proteolytic cleavage, which unmasks a tethered ...Ask Artificial Intelligence about these topicsTell me more about these topics.Natural Semantic
activated through proteolytic cleavage, which unmasks|Protease‐activated receptors (PARs) play a central role|protein‐coupled receptors are activated|platelet activation and|are activated through|(PARs) play a central role|are activated through proteolytic cleavage,|which unmasks a tethered ...|activation and thrombosis.|platelet activation and thrombosis. These G protein‐coupledThese phrases are extracted to provide meaningful, related search terms that help you explore topics naturally connected to this content.Back Link
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The role of protease-activated receptors (PARs) in the functioning of platelets and platelet-derived microparticles (PMPs) - Frontiers
Published: 18.08.2025, 06:19:44The role of protease-activated receptors (PARs) in the functioning of platelets and platelet-derived microparticles (PMPs) FrontiersProtease-activated receptors in vascular smooth muscle cells: a bridge between thrombo-inflammation and vascular remodelling - Cell Communication and Signaling
Published: 31.01.2025, 10:00:00Protease-activated receptors in vascular smooth muscle cells: a bridge between thrombo-inflammation and vascular remodelling Cell Communication and SignalingEndothelial protease-activated receptor 4: impotent or important? - Frontiers
Published: 09.01.2025, 19:28:49Endothelial protease-activated receptor 4: impotent or important? FrontiersProtease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity - PNAS
Published: 13.03.2022, 06:11:19Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity PNASDiscovery of quinazoline-benzothiazole derivatives as novel potent protease-activated receptor 4 antagonists with improved pharmacokinetics and low bleeding liability - ScienceDirect
Published: 15.12.2024, 10:00:00Discovery of quinazoline-benzothiazole derivatives as novel potent protease-activated receptor 4 antagonists with improved pharmacokinetics and low bleeding liability ScienceDirectSelective Inhibition of PAR4 (Protease-Activated Receptor 4)-Mediated Platelet Activation by a Synthetic Nonanticoagulant Heparin Analog | Arteriosclerosis, Thrombosis, and Vascular Biology - American Heart Association Journals
Published: 07.02.2019, 10:00:00Selective Inhibition of PAR4 (Protease-Activated Receptor 4)-Mediated Platelet Activation by a Synthetic Nonanticoagulant Heparin Analog | Arteriosclerosis, Thrombosis, and Vascular Biology American Heart Association JournalsStructural basis of tethered agonism and G protein coupling of protease-activated receptors | Cell Research - Nature
Published: 12.07.2024, 10:00:00Structural basis of tethered agonism and G protein coupling of protease-activated receptors | Cell Research NaturePlasmin-mediated Activation of Platelets Occurs by Cleavage of Protease-activated Receptor 4 - ScienceDirect
Published: 06.01.2021, 09:01:13Plasmin-mediated Activation of Platelets Occurs by Cleavage of Protease-activated Receptor 4 ScienceDirectIdentification of a Distinct Platelet Phenotype in the Elderly: ADP Hypersensitivity Coexists With Platelet PAR (Protease-Activated Receptor)-1 and PAR-4–Mediated Thrombin Resistance - American Heart Association Journals
Published: 16.06.2022, 10:00:00Identification of a Distinct Platelet Phenotype in the Elderly: ADP Hypersensitivity Coexists With Platelet PAR (Protease-Activated Receptor)-1 and PAR-4–Mediated Thrombin Resistance American Heart Association JournalsPlatelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation - Nature
Published: 07.12.2023, 10:00:00Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation NatureItems Tagged with 'protease-activated receptor 2'
Published: 08.02.2022, 17:59:00Researchers at New York University have demonstrated that protease-activated receptor 2 (PAR2) on epithelial cells of the colon continued after they were trafficked from the cell membrane.Ask Artificial Intelligence about these topicsTell me more about these topics.Natural Semantic
at New York University have demonstrated that protease-activated|protease-activated receptor 2 (PAR2) on epithelial cells|Researchers at New York University have demonstrated|protease-activated receptor 2 (PAR2) on|2 (PAR2) on|have demonstrated that protease-activated receptor 2 (PAR2) on|receptor 2 (PAR2)|cells of the colon continued|on epithelial cells|York University have demonstrated that protease-activatedThese phrases are extracted to provide meaningful, related search terms that help you explore topics naturally connected to this content.Back Link
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Published: 14.07.2004, 20:00:00No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2004 ASCO Annual Meeting. This abstract does not include a full text component.Ask Artificial Intelligence about these topicsTell me more about these topics.Natural Semantic
This abstract does not include a full|a full|Meeting Abstract|from the 2004 ASCO Annual Meeting. This abstract|Annual Meeting. This abstract|ASCO Meeting Abstract from the 2004 ASCO|financial relationships to disclose. This|ASCO Annual|ASCO Annual Meeting. This abstract|Abstract from the 2004 ASCO Annual Meeting.These phrases are extracted to provide meaningful, related search terms that help you explore topics naturally connected to this content.Back Link
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Vasculogenic mimicry in non-small cell lung cancer: a systematic review - Frontiers
Published: 24.07.2025, 10:00:00Vasculogenic mimicry in non-small cell lung cancer: a systematic review FrontiersSenescent lung fibroblasts in idiopathic pulmonary fibrosis facilitate non-small cell lung cancer progression by secreting exosomal MMP1 | Oncogene - Nature
Published: 11.12.2024, 10:00:00Senescent lung fibroblasts in idiopathic pulmonary fibrosis facilitate non-small cell lung cancer progression by secreting exosomal MMP1 | Oncogene NatureSmall but mighty: Platelets as multifunctional architects of tumor metastasis and immune regulation - Wiley Online Library
Published: 12.11.2024, 10:00:00Small but mighty: Platelets as multifunctional architects of tumor metastasis and immune regulation Wiley Online LibraryMicroRNA155 in non-small cell lung cancer: a potential therapeutic target - Frontiers
Published: 02.02.2025, 10:00:00MicroRNA155 in non-small cell lung cancer: a potential therapeutic target FrontiersUHRF1/DNMT1–MZF1 axis-modulated intragenic site-specific CpGI methylation confers divergent expression and opposing functions of PRSS3 isoforms in lung cancer - ScienceDirect
Published: 24.02.2023, 17:31:28UHRF1/DNMT1–MZF1 axis-modulated intragenic site-specific CpGI methylation confers divergent expression and opposing functions of PRSS3 isoforms in lung cancer ScienceDirectRegulatory mechanisms of PD-1/PD-L1 in cancers - Molecular Cancer
Published: 18.05.2024, 10:00:00Regulatory mechanisms of PD-1/PD-L1 in cancers Molecular CancerTMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer - Nature
Published: 03.04.2023, 10:00:00TMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer NatureUnleashing NK cells for cancer immunotherapy in lung cancer: biologic challenges and clinical advances - Journal of Experimental & Clinical Cancer Research
Published: 23.08.2025, 10:00:00Unleashing NK cells for cancer immunotherapy in lung cancer: biologic challenges and clinical advances Journal of Experimental & Clinical Cancer ResearchMechanisms of low MHC I expression and strategies for targeting MHC I with small molecules in cancer immunotherapy - ScienceDirect
Published: 28.02.2025, 10:00:00Mechanisms of low MHC I expression and strategies for targeting MHC I with small molecules in cancer immunotherapy ScienceDirectShear Stress Drives the Cleavage Activation of Protease-Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells - Wiley Online Library
Published: 03.07.2023, 10:00:00Shear Stress Drives the Cleavage Activation of Protease-Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells Wiley Online LibraryPhosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function
Published: 02.01.2023, 12:54:00Ying Lin, Jacob M. Wozniak, Neil J. Grimsey, Sravan Girada, Anand Patwardhan, Olivia Molinar-Inglis, Thomas H. Smith, John D. Lapek, David J. Gonzalez, JoAnn Trejo Proceedings of the National Academy ...Ask Artificial Intelligence about these topicsTell me more about these topics.Natural Semantic
Gonzalez, JoAnn Trejo Proceedings of the National Academy|Olivia Molinar-Inglis, Thomas H. Smith, John D. Lapek,|D. Lapek,|Anand Patwardhan, Olivia Molinar-Inglis, Thomas H.|David J. Gonzalez, JoAnn Trejo Proceedings of|D. Lapek, David J. Gonzalez, JoAnn Trejo|JoAnn Trejo Proceedings of the National|Jacob M.|D. Lapek, David J. Gonzalez, JoAnn Trejo Proceedings|Neil J. Grimsey, Sravan Girada, AnandThese phrases are extracted to provide meaningful, related search terms that help you explore topics naturally connected to this content.Back Link
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Endothelial protease-activated receptor 4: impotent or important? - Frontiers
Published: 09.01.2025, 19:28:49Endothelial protease-activated receptor 4: impotent or important? FrontiersAcetaminophen Overdose Reveals PAR4 as a Low-Expressing but Potent Receptor on the Hepatic Endothelium in Mice - American Heart Association Journals
Published: 03.10.2024, 10:00:00Acetaminophen Overdose Reveals PAR4 as a Low-Expressing but Potent Receptor on the Hepatic Endothelium in Mice American Heart Association JournalsPhosphoproteomic Analysis of Dopamine D2 Receptor Signaling Reveals Interplay of G Protein- and ฮฒ-Arrestin-Mediated Effects - ACS Publications
Published: 12.12.2022, 10:00:00Phosphoproteomic Analysis of Dopamine D2 Receptor Signaling Reveals Interplay of G Protein- and ฮฒ-Arrestin-Mediated Effects ACS PublicationsActivated protein C promotes protease-activated receptor-1 cytoprotective signaling through ฮฒ-arrestin and dishevelled-2 scaffolds - PNAS
Published: 02.03.2022, 00:27:04Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through ฮฒ-arrestin and dishevelled-2 scaffolds PNASSystems-level reconstruction of kinase phosphosignaling networks regulating endothelial barrier integrity using temporal data - Nature
Published: 16.11.2024, 10:00:00Systems-level reconstruction of kinase phosphosignaling networks regulating endothelial barrier integrity using temporal data NatureHeat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption - Science | AAAS
Published: 31.08.2021, 10:00:00Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption Science | AAASA cellular perspective of bias at G protein‐coupled receptors - Fernandez - 2020 - Protein Science - Wiley Online Library
Published: 16.04.2020, 10:00:00A cellular perspective of bias at G protein‐coupled receptors - Fernandez - 2020 - Protein Science Wiley Online LibraryEndothelial APC/PAR1 distinctly regulates cytokine-induced pro-inflammatory VCAM-1 expression - Frontiers
Published: 23.08.2023, 10:00:00Endothelial APC/PAR1 distinctly regulates cytokine-induced pro-inflammatory VCAM-1 expression FrontiersFluorescence resonance energy transfer (FRET) spatiotemporal mapping of atypical P38 reveals an endosomal and cytosolic spatial bias - Nature
Published: 08.05.2023, 10:00:00Fluorescence resonance energy transfer (FRET) spatiotemporal mapping of atypical P38 reveals an endosomal and cytosolic spatial bias Nature
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